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Older patients profit from intensified blood pressure treatment

Presented By
Prof. Jun Cai, FuWai Hospital, China
ESC 2021
The randomised controlled STEP trial revealed that lowering the systolic blood pressure (SBP) to below 130 mmHg in patients over 60 years led to a 26% reduction of adverse cardiovascular (CV) events [1]. A target SBP below 130 mmHg did not increase serious adverse events. “This study is important because it addresses a very simple question: When treating BP in older people, how low should we go,” expressed the trial discussant Prof. Bryan Williams (University College London, UK) [2]. STEP (NCT03015311) investigated intensive blood pressure (BP) treatment from 110 mmHg to <130 mmHg as SBP target versus standard therapy with SBP between 130 mmHg and <150 mmHg. The study enrolled 8,511 patients between 60–80 years of age who had no history of a prior stroke. BP medications consisted of olmesartan, amlodipine, and hydrochlorothiazide. The measuring of BP was eith...

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