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Retinal changes show promise in spotting Parkinson’s disease

JAMA Ophthalmology
Reuters Health - 31/12/2020 - Structural changes associated with Parkinson's disease (PD) seen via retinal imaging may present a novel biomarker for the disease, according to a cross-sectional study. As Dr. Sharon Fekrat and Dr. Dilraj S. Grewal told Reuters Health by email, "The changes we found in the small blood vessels in the retina and in the choroid may allow us to non-invasively assist in the diagnosis of PD by serving as an easily available screening tool." "While more research is required on this technology," they added, "such a non-invasive and rapid biomarker could also detect disease progression and help evaluate the efficacy of new interventions being investigated in clinical trials. " As reported online in JAMA Ophthalmology, Drs. Fekrat and Grewal of Duke University School of Medicine, Durham, North Carolina and colleagues studied 124 eyes of 69 patients with PD. A further 137 healthy participants (248 eyes) acted as controls. Using opti...

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