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Treating chronic mild hypertension during pregnancy leads to better outcomes

Presented By
Prof. Alan Tita, University of Alabama, USA
Conference
ACC 2022
Trial
CHAP
Doi
https://doi.org/10.55788/f538e95e
The multicentre, randomised CHAP trial showed that aggressively targeting blood pressure in pregnant women with mild chronic hypertension to be <140/90 mmHg provided better pregnancy outcomes, with no consequent harm to either mothers or babies. Presented by Prof. Alan Tita (University of Alabama, AL, USA), the Chronic Hypertension and Pregnancy (CHAP) trial (NCT02299414) aimed to assess the safety and efficacy of avoiding adverse pregnancy outcomes by treating pregnant women with mild chronic hypertension [1]. Prof. Tita pointed out that this is the largest, most diverse study conducted in pregnant women to date to address this major clinical question that has been debated for decades. The results were published simultaneously in the New England Journal of Medicine [2]. Enrolled were 2,408 women pregnant with a single foetus at <23 weeks of gesta...


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