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Bacterial decolonisation effective against radiation dermatitis

Presented By
Ms Yana Kost, Albert Einstein College of Medicine, NY, USA
Conference
ASCO 2022
Doi
https://doi.org/10.55788/52404bf7
Bacterial decolonisation of Staphylococcus aureus could effectively decrease the severity of radiation dermatitis and prevent moist desquamation in patients with breast or head-and-neck cancer who received radiotherapy. Moreover, this approach is safe, easy, and cost-effective, according to the authors. Ms Yana Kost (Albert Einstein College of Medicine, NY, USA) and colleagues demonstrated that nasal colonisation with Staphylococcus aureus prior to radiotherapy is a predictor of grade ‚Č•2 radiation dermatitis. Therefore, a randomised phase 2 trial (NCT03883828) was developed to compare a strategy of bacterial decolonisation with standard-of-care in patients (n=80) with breast cancer or head-and-neck cancer who were planned to receive fractionated radiotherapy (‚Č•15 fractions) [1]. Patients in the bacterial decolonisation arm received intra...


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