Asthma & COPD
Most severe asthma patients are candidates for biologic therapy on a global scale
Gabapentinoids increase risk of exacerbations in COPD
Future treatment of fatigue in COPD: 4 possible targets identified
Tapering from high-dose inhaled corticosteroids possible in most asthma patients treated with benralizumab
Tezepelumab therapy: hints toward a disease-modifying effect?
Digital inhaler programme improves asthma control also in the long term, but not long-term adherence

Wildfire smoke in New York: adapting to a new respiratory reality
Vitamin D for asthma protection: what is the optimal timing?
Practice-changing results for ensifentrine in COPD
Alvelestat for AATD meets primary endpoints in phase 2 trial
Fewer exacerbations with dupilumab in COPD with type 2 inflammation
Remarkable results for novel biologic therapy for asthma
Efficient detection of AECOPD with at-home vital signs monitoring
Success for fluticasone furoate plus vilanterol in uncontrolled asthma

Antibiotics cause increased risk of wheezing in severe RSV bronchiolitis

Tezepelumab in asthma: mucus plugging down, lung function up
Digital asthma intervention improves health and reduces costs

Digitally enhanced therapy lowers treatment burden and costs in severe asthma
Mepolizumab beneficial for patients with severe eosinophilic asthma
Icenticaftor achieves results on top of triple inhalation therapy in COPD
STARR2: A new approach for treating COPD exacerbations
COPD medication not effective in symptomatic smokers with preserved spirometry
Do digital tools improve physical activity in COPD?
Hyperpolarised gas MRI ready for clinical use

Physical activity improves asthma control
Tailored exercise needed for COPD patients
Asthma increases risks around delivery
PRO-ART study: unravelling the link between asthma and subfertility
Early-onset and uncontrolled asthma: strong association with recurrent pregnancy loss
Severe asthma in the spotlights
Common comorbidities in severe asthma
Targeting treatable traits allows a personalised approach to management of (severe) asthma
Exercise-induced laryngeal obstruction (EILO) is often misdiagnosed
The ULANC Group: working together in CRSwNP/asthma
E-cigarettes impose detrimental effects on health
Effects of passive vaping in COPD patients

MANDALA and DENALI pattern success for albuterol-budesonide in asthma
ACOUSTICS data sounds good for adolescent asthma exacerbations

Type 2 asthma in children managed by dupilumab, despite atopic comorbidities
NAVIGATOR steers asthma patients to tezepelumab

High-intensity interval training slashes daily corticosteroids in asthma
Three’s a crowd for triple therapy in COPD
Higher 1-year COPD mortality after hospitalisation for White patients
Reducing dyspnoea in chronic lung disease through weight loss

CT-evident mucus plugs in COPD associated with death
Home-based rehabilitation improves COPD: a randomised study
No screening evidence for COPD
Telemedicine has mixed influence on costs of asthma care

Dupilumab cuts severe asthma exacerbations by 59% in children aged 6 to 11
Understudied low-lung-function state tied to increased risk of respiratory problems and death
Rhinovirus bronchiolitis increased risk of recurrent wheezing and asthma
Livestock farming affected the airway microbiome of COPD patients

Reduction of COPD severe acute exacerbations by candidate vaccine

Biomarkers do not discriminate severe from severe uncontrolled asthma
Increased blood neutrophiles in patients with obesity and asthma
Dynamics of environmental pollution during and after COVID-19 lockdown
Blood inflammatory phenotypes associated with clinical symptoms of asthma
Paradoxical bronchospasm may go unrecognized in patients with COPD or asthma

Circadian system implicated in asthma worsening at night
Restoring pulmonary endothelial cells reverses emphysema in mice
Vaping identified as risk factor for asthma
Obesity: A risk factor for new-onset asthma and worse asthma control
Metabolic dysfunction and lung disease: children are no small adults
Possible aetiologies for COPD exacerbations – more evidence is needed
Does COPD plus COVID-19 equal higher mortality?
Biomarkers for acute exacerbations in COPD are required
Severe exacerbations: A key driver of all-cause mortality in COPD patients
Men and women with COPD differ in many ways

Younger adults with COPD at higher health risk than previously thought
“As-needed” inhaled corticosteroid therapy for mild asthma – what is the evidence?

IL-4/13 blocker successful in treatment of paediatric moderate-to-severe asthma

Benralizumab lives up to its phase 3 results in real-world findings
Tezepelumab – good success rates in various types of severe asthma
Frequent snoring tied to increased asthma symptoms, health care use in kids
HRT tied to increased risk of severe asthma exacerbation
Dupilumab an option when other targeted agents fail in aspirin-exacerbated respiratory disease
Bronchial thermoplasty benefits for uncontrolled asthma sustained at 10 years
Benralizumab improves health-related quality of life in severe eosinophilic asthma
Disinfecting during pandemic puts asthmatics at risk
Children with exercise-induced respiratory symptoms may get conflicting diagnoses
Anti-IL-5 biologics effective for up to two years in severe asthma, but residual disease remains
Smartphone-based cough detection helpful in predicting asthma deterioration
The role of chronic symptoms as early biomarkers of COPD development
Urgent call for studies in COPD patients aged 40-60 years
Nasal high-flow therapy: a novel treatment option for hypercapnic COPD patients

Exacerbation history is a reliable predictor of future exacerbations
Singing training effective as physical rehabilitation in COPD

Mild asthma: A fundamental change in management
Dupilumab shows long-term efficacy in asthma patients
Severe asthma: Oral corticosteroids maintenance therapy associated with toxicity
First-in-class tyrosine kinase inhibitor shows promise in severe asthma
Predicting individual effectiveness of biologics in severe asthma
Current prediction tools underestimate exacerbation risk of severe COPD patients
IL-5 antagonist showed efficacy in chronic rhinosinusitis with nasal polyps
Treatment according to genotype: The future of asthma therapy?
Asthma rescue with budesonide-formoterol cuts short-term flare risk
For COPD with nocturnal hypoxemia, nighttime oxygen has no survival benefit
Limited evidence supports escalation of therapy for acute asthma exacerbations in kids
Smart shirt as a device to measure tidal volumes in real-life setting
COPD patients harbouring Pseudomonas Aeruginosa face high risk of hospitalisation
Exercise with virtual reality beneficial for COPD patients
One blood eosinophil count is sufficient to guide ICS therapy
Female COPD patients frequently suffer from anxiety and depression
COPD patients do not benefit from azithromycin therapy longer than a year
Pneumococcal vaccines: an effective way to reduce COPD hospitalisations
Dual bronchodilation improves ventilation dynamics in COPD patients

Holistic view on asthma

Dupilumab improves outcomes in patients with severe chronic rhinosinusitis with nasal polyps and comorbid asthma
Benralizumab does not ameliorate COPD exacerbations (GALATHEA/TERRANOVA trials)
Ensifentrine for COPD maintenance treatment

Treatable traits in chronic inflammatory airway disease: back to basics
Aclidinium bromide delays COPD exacerbation without increased MACE risk

[Long Read] Current Look on Asthma
Landmark triple therapy trials
Endoscopic treatment of asthma

ICS: to use or not to use?
